<img src="https://ml.globenewswire.com/Resource/Download/f678abe0-8882-4b07-9419-be2c36c9a31d?size=2" nborder="0" align="left" hspace="5" vspace="5" title="A.D.A.M. Innovations.jpg" alt="A.D.A.M. Innovations"/>New models for asthma, atopic dermatitis and chronic obstructive pulmonary disease (COPD) expand GeneAI Forecast to 18 conditions, alongside resting heart rate integration from health apps and wearable devices. TOKYO, Sept. 16, 2026 <a href="https://www.globenewswire.com" target="_blank">(GLOBE NEWSWIRE)</a> -- A.D.A.M. Innovations Co. (Japanese corporate name: Genesis Healthcare Co.), a genomic intelligence, AI and precision health company, today announced an expansion of its GeneAI Forecast service with three new chronic disease risk assessment models - asthma, atopic dermatitis and chronic obstructive pulmonary disease (COPD) - and the integration of average resting heart rate as a new digital biomarker. With this update, GeneAI Forecast now includes 18 disease risk assessments spanning lifestyle-related risks, chronic and progressive diseases, and cancer risks, combining genomic information with health and physiological data. Expanding to Chronic Diseases Asthma, atopic dermatitis and COPD are chronic conditions influenced by a combination of genetic, environmental and lifestyle factors. The three new assessments provide GeneAI Forecast users with additional insights into their genetic factors associated with these conditions, supporting greater awareness and more informed preventive health management. GeneAI Forecast leverages A.D.A.M. Innovations’ genomic intelligence capabilities and extensive genomic datasets, together with scientific and clinical evidence and multimodal health data, to generate increasingly personalized assessments of individual health risks. <img alt="GeneAI Forecast - Risk Assessment Models" height="415" src="https://ml.globenewswire.com/Resource/Download/6f012784-bb1f-4abc-af6e-54137c6a4e4a/image1.png" width="600" data-dpi="220" data-caption="GeneAI Forecast - Risk Assessment Models" data-filename="image1.png" /> GeneAI Forecast - Risk Assessment Models Connecting Genomics with Real-World Health Data GeneAI Forecast already combines genomic information with key health biomarkers, including BMI, blood pressure and glucose levels, to provide a more comprehensive assessment of individual health risk. This update adds average resting heart rate as a new digital biomarker, introducing an additional layer of physiological information into the platform. Average resting heart rate is associated with cardiovascular fitness, autonomic nervous system activity, stress, recovery and overall health status. Through integration with leading health applications and wearable devices, GeneAI Forecast can incorporate resting heart rate information alongside other health and behavioral data, including average daily step counts. The platform builds on its existing integration with Apple Health and Google Fit, enabling connected health data to complement an individual’s genomic information and provide a more comprehensive view of their health profile over time. “GeneAI Forecast is evolving from a static view of genetic predisposition towards a more dynamic understanding of health risk,” said Michel Mommejat, President and Chief Innovation Officer of A.D.A.M. Innovations. “By expanding our risk assessment models and integrating physiological information from connected health technologies, we are bringing genomic intelligence together with real-world health data. Our goal is to give individuals a more personalized and dynamic view of their health and support a more proactive approach to prevention.” GeneLife consumers can access GeneAI Forecast, including the new chronic disease models and resting heart rate biomarker, through the Genesis CONNECT and WGS CONNECT subscription plans. For additional information, visit: <a href="https://www.globenewswire.com/Tracker?data=STGowwc51YR9yogLQNuMCpvkqC9WsJR09DXQBBE94uVwV59iA6lbJntlFrct3agfVU7bHZWMinF1DYrn-C-X3VcIWu8ixjxBruEKYomquvaS3rcY1S_3mtfUElNECqMc" rel="nofollow" target="_blank" title="www.adam-innovations.com">www.adam-innovations.com</a> <a href="https://www.globenewswire.com/Tracker?data=QKab-CkxZmUYyrkWX0O-mHh2CdMWVwzDziNgtaTLHuwNGQCy3GquFu9cCIMcBOLH93mwsFKPeFUiyqiuTGpwgMzuwHo3u_YaU-2SW_K1rsk=" rel="nofollow" target="_blank" title="www.genelife.jp">www.genelife.jp</a> Corporate media contact: Email: <a href="https://www.globenewswire.com/Tracker?data=HK3ZfGJMbYfo-WYUnbOPGCjXQodQI0u8A0yRa-5o2m-kIDkRUOPgDRJNLhLBEzXugFwxfKfQVic8maTKRqcUE1rUbvMZ801bJS1LdlycIyF6aeZfkXROy00L_1woCvfK" rel="nofollow" target="_blank" title="press@adam-innovations.com">press@adam-innovations.com</a> About A.D.A.M. Innovations Co. Founded in 2004 in Tokyo, A.D.A.M. Innovations Co. (Japanese corporate name: Genesis Healthcare Co.) is building the world's leading genomic intelligence platform by integrating genomics, multimodal biological and health data, artificial intelligence, and secure data technologies to transform data into actionable solutions. Leveraging one of Japan's largest genomic datasets, the Company develops technologies that advance healthcare and drive innovation across life sciences, pharmaceuticals, consumer industries, agriculture, and research. Having conducted more than 2.9 million genetic tests, A.D.A.M. Innovations maintains the largest commercial R&amp;D genomic database of the Japanese population.  A.D.A.M. Innovations is committed to advancing personalized healthcare, precision medicine, scientific discovery, and the future of human health, while making a meaningful impact on people's lives. About GeneLife GeneLife is the consumer genomic brand of A.D.A.M. Innovations. GeneLife brings genetic testing directly to individuals through at-home kits and e-commerce channels, delivering personalized health and wellness insights to empower better living and longevity. About GeneAI Forecast GeneAI Forecast is A.D.A.M. Innovations’ AI-powered predictive health platform that combines genomics, multimodal health data, digital biomarkers and artificial intelligence to assess where an individual fall within predefined disease risk or health status categories based on medically and scientifically grounded, objectively developed and validated predictive models, and to provide preventive health insights. GeneAI Forecast is intended to support health awareness and provide individuals with informational insights into potential health risks. It is not intended to provide medical diagnoses or treatment recommendations. With the latest expansion, GeneAI Forecast includes 18 predictive models across four categories: Lifestyle-related risks: <ul type="disc"><li style="margin-top:5pt; margin-bottom:5pt;">Hypertension</li><li style="margin-top:5pt; margin-bottom:5pt;">Type 2 Diabetes</li><li style="margin-top:5pt; margin-bottom:5pt;">Myocardial Infarction</li><li style="margin-top:5pt; margin-bottom:5pt;">Stroke</li><li style="margin-top:5pt; margin-bottom:5pt;">Chronic Kidney Disease </li></ul> Chronic diseases:  <ul type="disc"><li style="margin-top:5pt; margin-bottom:5pt;">Asthma (new)</li><li style="margin-top:5pt; margin-bottom:5pt;">Atopic Dermatitis (new)</li><li style="margin-top:5pt; margin-bottom:5pt;">Chronic Obstructive Pulmonary Disease (COPD) (new)</li><li style="margin-top:5pt; margin-bottom:5pt;">Irritable Bowel Syndrome (IBS)</li><li style="margin-top:5pt; margin-bottom:5pt;">Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) </li></ul> Progressive diseases:  <ul type="disc"><li style="margin-top:5pt; margin-bottom:5pt;">Osteoarthritis</li><li style="margin-top:5pt; margin-bottom:5pt;">Osteoporosis</li></ul> Cancer risks: <ul type="disc"><li style="margin-top:5pt; margin-bottom:5pt;">Lung Cancer</li><li style="margin-top:5pt; margin-bottom:5pt;">Stomach Cancer</li><li style="margin-top:5pt; margin-bottom:5pt;">Colorectal Cancer</li><li style="margin-top:5pt; margin-bottom:5pt;">Pancreatic Cancer</li><li style="margin-top:5pt; margin-bottom:5pt;">Breast Cancer (female-specific)</li><li style="margin-top:5pt; margin-bottom:5pt;">Prostate Cancer (male specific)</li></ul> Key biomarkers: <ul type="disc"><li style="margin-bottom:2pt;">BMI</li><li style="margin-bottom:2pt;">Blood pressure</li><li style="margin-bottom:2pt;">Glucose levels</li><li style="margin-bottom:2pt;">Average resting heart rate (new)</li><li style="margin-bottom:2pt;">Average daily step count </li></ul> Average resting heart rate and average daily step count can be imported from Apple Health and/or Google Fit or input manually. GeneAI Forecast Disclaimer:  GeneAI Forecast is intended for informational and health awareness purposes only and does not provide medical advice, diagnoses or treatment recommendations. Its AI-assisted analyses and risk assessment models are subject to internal validation and appropriate human oversight. Results represent risk assessments within predefined risk categories established on the basis of medically and scientifically grounded criteria, based on available genomic, health and other data and should not be interpreted as a prediction or confirmation that an individual will or will not develop a particular condition. Users should consult a qualified healthcare professional regarding medical concerns or decisions. Forward-Looking Statements This press release contains forward-looking statements regarding A.D.A.M. Innovations’ technologies, products, services and business plans, including the development, functionality, performance, availability and future expansion of GeneAI Forecast, its risk assessment models, digital biomarker integrations and connected health capabilities. These statements are based on current expectations, assumptions and information available to the Company and involve risks, uncertainties and other factors that could cause actual results, performance, functionality, availability or developments to differ materially from those expressed or implied. Such factors include, among others, the results of ongoing development and validation activities, technological and scientific developments, data availability and quality, third-party platform and device integrations, regulatory requirements, market adoption and other risks and uncertainties affecting the Company’s business. A.D.A.M. Innovations undertakes no obligation to update or revise any forward-looking statements, except as required by applicable law. GeneLife and GeneAI Forecast are registered trademarks of A.D.A.M. Innovations Co. Apple Health is a trademark of Apple Inc. Google Fit is a trademark of Google LLC. 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A.D.A.M. Innovations Expands GeneAI Forecast With New Chronic Disease Risk Assessment Models and Connected Biomarker Integration

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