<img src="https://ml.globenewswire.com/Resource/Download/d8f3f116-ccaf-4c51-af12-154863973974?size=2" nborder="0" align="left" hspace="5" vspace="5" title="CN100 logo.jpg" alt="Canadian National Railway Company"/>MONTREAL, Sept. 17, 2026 <a href="https://www.globenewswire.com" target="_blank">(GLOBE NEWSWIRE)</a> -- Ghislain Houle, Executive Vice-President and Chief Financial Officer of CN (TSX: CNR) (NYSE: CNI), will address the 25th Annual CIBC Eastern Institutional Investor Conference on September 24, 2026, at 8:00 a.m. Eastern Time (ET). CN will provide a live webcast via the Investors section of its website at <a href="https://www.globenewswire.com/Tracker?data=yktg5BHe9aFB6Ki4MaIdRtxMhZIOqjUYQ3eDtKaJpOLhGBRbrTJFrZYDpu-8dv9dI0SrDdVJCIpJXzntUO9-COaga1DJ55ZlJrNmhN1r5Qo=" rel="nofollow" target="_blank" title="www.cn.ca/investors">www.cn.ca/investors</a>. A replay of the webcast will be available following the event. About CN CN powers the economy by safely transporting more than 300 million tons of natural resources, manufactured products, and finished goods throughout North America every year for its customers. With its nearly 20,000-mile rail network and related transportation services, CN connects Canada’s Eastern and Western coasts with the U.S. Midwest and the U.S. Gulf Coast, contributing to sustainable trade and the prosperity of the communities in which it operates since 1919. Contacts: <table style="border-collapse: collapse; width:100%; border-collapse:collapse ;"><tr><td style="vertical-align: top ; ">Media</td><td style="vertical-align: top ; ">Investment Community</td></tr><tr><td style="vertical-align: top ; ">Ashley Michnowski</td><td style="vertical-align: top ; ">Jamie Lockwood</td></tr><tr><td style="vertical-align: top ; ">Senior Manager</td><td style="vertical-align: top ; ">Vice-President</td></tr><tr><td style="vertical-align: top ; ">Media Relations</td><td style="vertical-align: top ; ">Investor Relations &amp; Special Projects</td></tr><tr><td style="vertical-align: top ; ">(438) 596-4329</td><td style="vertical-align: top ; ">(514) 399-0052 </td></tr><tr><td style="vertical-align: top ; "><a href="mailto:media@cn.ca" rel="nofollow" target="_blank" title="media@cn.ca">media@cn.ca</a></td><td style="vertical-align: top ; "><a href="mailto:investor.relations@cn.ca" rel="nofollow" target="_blank" title="investor.relations@cn.ca">investor.relations@cn.ca</a> </td></tr></table> <img alt="" src='https://ml.globenewswire.com/media/MzRmYzcxZWYtYjhkNy00NmRjLTg2OWUtN2E0ZjNlYzE2YWY1LTEwMTgxMTYtMjAyNi0wOS0xNy1lbg==/tiny/Canadian-National-Railway.png' referrerpolicy='no-referrer-when-downgrade' />

Ghislain Houle to address the 25th Annual CIBC Eastern Institutional Investor Conference on September 24

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